Non-specific rhino-sinusitis by Klaus Mees (ISBN-13: 9783540608530)
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Non-specific rhino-sinusitis by Klaus Mees (ISBN-13: 9783540608530)

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Non-specific rhino-sinusitis by Klaus Mees

Over 30% of all respiratory infections originate primarily in the paranasal sinuses and, together with inflammation of the ethmoid cells and maxillary sinuses, are among the most common diseases in an ENT practice. The focus of the 1st Sylt Secretolysis Talks, which were initiated by Pohl-Boskamp and which are to take place every 2 years in the future, were the non-specific defence mechanisms of the sinunasal mucosa. In front of an interdisciplinary forum, their complex disorders and the current therapeutic possibilities were presented and discussed. An important prerequisite for the non-specific immune defence of the respiratory mucosa is the intactness of the mucociliary clearance. This can be damaged in different ways, on the one hand by direct influence on the ciliary epithelium, but also indirectly by a viscosity change in the periciliary serous nasal secretion. Viral infections can significantly reduce the frequency of strokes and even bring them to a standstill, but decongestant alpha-adrenocetor agonists (xylometazoline) and possibly also some preservatives often present in nasal sprays also have an inhibiting effect on ciliary activity. In addition, the viscosity of the nasal secretion increases considerably in the case of inflammation, on the one hand as a result of the entciindal exudation and on the other hand as a result of the decreasing pH-dependent degree of hydration of the proteins dissolved in the nasal secretion (secretory IgA, glycoproteins, cellular enzymes, etc.). The goal of effective sinusitis therapy must therefore be the restoration of the disturbed mucosiliary clear-VI preface in addition to locally decongestant measures and the elimination of bacterial superinfections. Numerous defined chemical and plant secretolytics are available to stimulate the ciliary activity of the respiratory epithelium as well as the secretion capacity of the goblet cells and the subepithelial glands.

Book details

ISBN 13 9783540608530
ISBN 10 3540608532
Author Klaus Mees
Condition New
Binding Type Paperback
Publisher Springer
Year published 1996-10-15
Number of pages 176
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.

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