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| Language | English |
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Metal Compounds in Cancer Therapy by Sp Fricker
The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo- platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora- tories throughout Europe and America and represent the many disci- plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.| ISBN 13 | 9789401045452 |
|---|---|
| ISBN 10 | 9401045453 |
| Author | Sp Fricker |
| Condition | New |
| Binding Type | Paperback |
| Publisher | Springer |
| Year published | 2012-10-29 |
| Number of pages | 256 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
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